Title

Mechanical Interferometry of Nanoscale Motion and Local Mechanical Properties of Living Zebrafish Embryos

Document Type

Article

Publication Date

7-10-2009

Publication Title

American Chemical Society Nano

Department

Neuroscience

Abstract

We present an interferometric imaging technique that permits local measurement of mechanical properties and nanomechanical motion in small living animals. Measurements of nanomechanical properties and spatially resolved pulsations of (Danio rerio) embryo, an important model organism. We also used magnetic microreflectors to conduct contact nanomechanical indentation measurements of the stiffness of the embryonic eye.

Volume

8

Issue

3

pp.

2090-2094

ISSN

1936-0851

nn-2009-00473y_0004.gif (66 kB)
Figure 1. (a) Anatomy of a 3 day old (3 dpf) embryonic

nn-2009-00473y_0001.gif (25 kB)
Figure 2. (a) Schematic of the experiment. (b) Time series plot of the displacement of the microreflector

nn-2009-00473y_0002.gif (52 kB)