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Abstract

Headache pain affects a large portion of the population and significantly reduces quality of life. Stress has been implicated as a cause in many headache disorders, and this study investigates how stressful events affect subjects with chronic headache pain. Ten days after a stressful event, there was a significant change in perceived headache pain, though pain increased for some and decreased for others. Stress-related release of the hormone thyroxine may be a mediator for chronic pain states.

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