Synthesis of Pyridone Ligands and Iron Precursors for the Development of Iron-based Hydrogenation Catalysts

Faculty Advisor

Boisvert, Luc

Area of Study

Science and Mathematics

Publication Date

Summer 2015


Green chemistry is concerned with the development of safer, more efficient, and more environmentally acceptable chemical products and processes. An important aspect of green chemistry is the reduction of chemical waste. Catalysis is essential to achieving such a transformation. Hydrogenation is an example of an industrially important catalytic process. Hydrogenation reactions are common in the pharmaceutical industry as they provide a cost-effective and reliable approach to a wide range of compounds. However common hydrogenation catalysts are composed of expensive and toxic metals. The goal this research is to develop hydrogenation catalysts, based on iron, that will be less expensive and more environmentally acceptable than catalysts currently used in the pharmaceutical industry. The overall plan of this research is to first optimize the synthesis of organic ligands. Then, using a suitable iron complex precursor that is synthesized, attach the ligands to an iron center to form a hydrogenation catalyst. Finally, the hydrogenation activity of any catalyst formed will be tested.


University of Puget Sound

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