Faculty Advisor

Dasher, William

Area of Study

Science and Mathematics

Publication Date

Summer 2011


The main focus of this research was on derivatizing cinchonidine's secondary hydroxyl group with various ester functional groups 2-hydroxyphenylacetic acid, 3-hydroxyphenylacetic acid, and 4-hydroxyphenyl acetic acid in order for them to be used as chiral catalysts, which are important in the production of pharmaceuticals. Simple synthesis methods were shown to accurately create each derivatized catalyst compound for testing in asymmetric Micheal reactions to determine each compound's feasibility as an effective chiral catalyst.


University of Puget Sound