Area of Study
Science and Mathematics
Bdellovibrio bacteriovorus is a predatory Gram-negative Deltaproteobacterium that attacks and invades larger Gram-negative bacteria devouring them from within (Sockett, 2004). Enzymatic results obtained in the 1970s suggest that Bdellovibrio relies on its tricarboxylic acid (TCA) cycle and the oxidation of prey cell derived amino acids (Hespell, 1976). However, annotation of the published genome of Bdellovibrio HD100 revealed that it lacked numerous genes involved with the degradation of amino acids (Rendulic, 2004). Thus it is of great interest to determine if Bdellovibrio can degrade amino acids. If it can, new genes related to the degradation of amino acids will be discovered thanks to the unique genome of Bdellovibrio. If not, new research into why Bdellovibrio is so particular about which amino acids it degrades can be started.
Anderson, Scott, "Investigating the Bacterial Predator Bdellovibrio’s Ability to Degrade Aspartate" (2011). Summer Research. 113.
University of Puget Sound